Wednesday  March  12, 2008


6.00 pm                        Sala  Orelli,    Ancient   Monastery  of  Capuchins

                                    Alta Scuola Pedagogica [ASP]

                                                Reception of participants and registration


                                                                          Aula  Magna  ASP

7.00 pm                        session I    

                                    Welcome/ Opening of the Fifth International Symposium

                                               < Fractals in Biology and Medicine >


Invited speaker:  Angela Downs Rigaut, St Marc-le-Blanc, F

 < Jean Paul Rigaut: a personal portrait>                                               (l)


Invited speaker: Gabriel Landini, Birmingham, UK

                                        <Jean Paul Rigaut’s contribution to  the  Fractal Geometry
                                                     in Biology
>                                                                                                (l)


 8.00 pm                      Ancient Monastery  ASPConvivial Party


Thursday 13  March 2008

Aula  Magna  ASP


9.00 am                The Scientific Committee: Introductory Remarks


oral presentations


9.10 am                Session  II

Chairman: Fritz Albregtsen  Oslo  N

Gabriel  Landini,  David A. Randell
Oral Pathology Unit, School of Dentistry, The University of Birmingham,UK
The complexity of cellular neighbourhoods.                                            (p)

Venus Sharifi- Salamantian 
Paris  France
On stereological estimation in the presence of spatial heterogeneity            (p)

Rasha Fadel Abu Eid
The University of Jordan, Amman  Jordan
Architectural changes associated with ageing
of the normal oral buccal  mucosa                                                       (p)

Marielda Cataldi (1), Francesca Carella (1),Gionata De Vico (1), Stefano Beltraminelli (2), Gabriele A. Losa (2)
(1) Napoli Università Federico II, 80134  Napoli  Italy; (2) Institute of Scientific Interdisciplinary Studies, 6600 Locarno  Switzerland
The expression of beta catenin in relation to the fractal organization of canine  trichoblastoma tissues.                                                                     (p)


10.50 am                Pause

11.10 am                Session  III 

                                       Chairman:   Konradin Metze,  Campinas  BR

 Mauro Tambasco
 Department of Oncology, University of Calgary, Calgary,  Canada
 Local Variations in the Architectural Complexity of
Histology Specimens       (p)

 Giorgio Bianciardi 
 University of Siena, Siena   Italy
 Phase transition of vascular network architecture in human pathologies        (p)

Herbert F. Jelinek*, Nebojša T. Milošević, Dušan Ristanović
*Charles Stuart University, Albury Australia; University of Belgrade, Belgrade Serbia
Fractal dimension as a tool for classification of rat retinal  ganglion cells      (p)

Invited speaker: Nebojša T. Milošević,   Dušan Ristanović
Department of Biophysics, School of Medicine, University of Belgrade,
Belgrade,  Serbia
The box-counting method as an efficient tool for 2D fractal analysis
of neuronal dendritic arbor                                                                  (l)


  1.00-3.00   pm      Intermezzo


  3.00 pm                Session  IV

      Chairman : Herbert F. Jelinek   Albury  AU
Rangaraj M. Rangayyan
      of Electrical and Computer Engineering
  Schulich School of
      Engine University of Calgary,
Calgary, Alberta,  University of Calgary,
      Calgary,  Canada 
      Detection of architectural distortion in prior mammograms using Gabor filters,
      phase portraits, fractal analysis, and texture analysis.                             (p)

Konradin Metze*, Randall Luis Adam**, Maria Luiza de Castro Valladào***, Karime Cury Scarpelli****, Neucimar J. Leite**, Irene G.H. Lorand-Metze ******Department of Pathology, Faculty of  Medicine, State University of Campinas, Campinas; **Institute of Computing , State University of Campinas; ***Postgraduate Course in Medical Pathophysiology, Faculty of Medicine, State University of Campinas;**** Postgraduate Course in Medicine, Faculty of Medicine; *****Department of Medicine, Faculty of Medicine, State University of Campinas (UNICAMP), Brazil.
The goodness of fit of the  log-log regression of the Minkowski-Bouligand algorithm applied to routine cytology as a prognostic  factor                      (p)

Przemko Waliszewski 
Department of Urology, Klinikum Fichtelgebirge 95615 Marktredwitz,  Germany
Fokker-Planck equation and coupling in modelling of tumour growth.            (p)

Rosario  Santoro (1), Giorgio  Turchetti (2), Ugo Albisinni (3),
Fiorenzo Marinelli (1)

(1)Molecular Genetic Institute, IOR (IGM-CNR)40136 Bologna, Italy
(2) Dept of Physics, Bologna University, (3) Radiology Inst. IOR Bologna,  Italy 
Multifractal analysis in radiographs of osteoporotic bone tissue.               

A. Ben Abdallah (1), H. Hakkari (1), I. Bhouri (2), P.Dubois (3),
M.H. Bedoui 
(1) Laboratoire de biophysique, TIM, Faculté de Médecine, Monastir, Tunisie.(2) Unité  de  recherche  Multifractals  et  Ondelettes, TIM, Faculté des  Sciences de Monastir, Tunisie (3) Laboratoire de biophysique, INSERM, U703, Lille, France.
Lacunarity estimation for analysis of 3D images of  trabecular  bone          (p) 




6.00 pm                  Aula Magna ASP 

 Invited speaker: Marino Viganò, Locarno  CH, Milano  I
 Castle's Rivellino (1507): Leonardo at Locarno ?                                    (l)

6.40 pm                  Visconti Castle: guided visit of the bastion
                                        < Rivellino -Leonardo 
da  Vinci  ?  > 
8.00 pm                  Visconti  Castle:  Casorella,  Sala delle Udienze  
                              Convivial party:  under the hospitality 

of  Madame Dr. Carla Speziali,
                              and the Municipality of the City of Locarno




 Friday 14 March 2008

9.00  am                           Session  IV 

                                       Chairman:  Gabriel Landini   Birmingham  UK 

                                       Giovanni Dietler
                             Laboratoire de Physique de la Matière Vivante, Ecole Polytechnique   
                             Fédérale de Lausanne, Lausanne, Switzerland
                             Polymer Physics versus DNA Topology.                                                (p)

Nadja Kanduc, Giovanni M. Capone
Department of Biochemistry and Molecular Biology, University of Bari,Italy
The similarity profile  of the human proteome as a fractal dimension.        (p)

Loretta Ichim*° , Radu Dobrescu*
*Faculty of Control and Computers, Politehnica University of Bucharest, Romani, °Stefan S. Nicolau Institute of  Virology, Romanian Academy, Romania
Using fractal analysis for determination of the size  distribution of HeLa cellular nuclei  in spectrophotometric images.                                                 (p)  

Konradin Metze*, Randall Luis Adam**, Neucimar  J. Leite**,  Irene G.H.

*Department of Pathology, Faculty of Medicine, State University of Campinas (UNICAMP), Campinas, Brazil;**Institute of Computing, State University of Campinas***Department of Medicine, Faculty of Medicine, State University of Campinas,  Brazil
A comparison of different methods for the evaluation of the fractal dimension of surface: a study based on synthetic images and on chromatin structure in cytology.                                                                                       (p)

                Fiorenzo Marinelli (1), Giorgio Tuchetti (2), Nicoletta  Zini (1),
                 Rosario Santoro (1)

1) Molecular Genetic Institute, IOR (IGM-CNR) 40136 Bologna   Italy
                2 ) 
Dept of Physics Bologna University,  Bologna   Italy
Multifractal analysis of chromatin during apoptosis.                                 (p)     


10.40  am              

11.10  am               Session  V   

Chairman    Georges  Delides    Heraklion    G      

Wlodzimierz  Klonowski
Polish Academy of Sciences, Warsaw  Poland
Simple fractal method of assessment of histological texture for medical diagnosis.                                                                                     (p)

M. M. Bouguerra, M.A. Alimi 
REGIM, ENIS, BP W,, University of Sfax , Sfax,  Tunisia 
Fractal analysis limitation to describe and classify (normal and pathological cases) of human retinal blood vessels.                                                (p)
Catalin-Iulian Chiurciu (2), Ion Dina (3), Camelia-Doina Vrabie(3),
Marius Cornitescu (1)
(1) "Stefan S. Nicolau" Institute of Virology, Bucharest; (2) "Dr. C. Chiurciu" Medical Praxis, Bucharest; (3) "St. John" Emergency Hospital, Bucharest, Romania.
Structure recognition in human optical microscopy specimens using the fractal analysis of the spatial colour density distribution.

Julia Maria Kroepfl (a), Roland Sedivy (b), Helmut Ahammer  (a)
(a) Institute of Biophysics, Medical University of Graz,  8010 Graz, Austria
(b) Landesklinikum  St. Pölten,  3100 St. Pölten, Austria
The importance of the Fast Fourier dimension and texture statistics for a medical classification problem.                                                          (p)

Dimitri Voronine (2),  Sonal O. Uppal (1), Elizabeth Wendt (3),
Carol A. 
Heckman (3)
(1) Lerner Research Institute, Cleveland, USA;  2) Institut für Physikalische  Chemie,  Wuerzburg. 
Germany;  3) Department of Biological  Sciences,  Cleveland,  USA 
Morphological fractal analysis of cell shape in cancer chemotherapy.

 1.00-3.00  pm        Intermezzo


 3.00  pm                Session  VI     

Chairman:  Mircea V. Rusu       Bucharest   R

Invited speaker: Ralf Metzler (1,2), 
Michael A.  Lomholt   (3) 
(1) Physics Department, Technical University of Munich, D-85747 Garching, Germany;(2) Center for NanoScience, Ludwig Maximilians Universität, Geschwister-Scholl-Platz 1,D-80539 Munich, Germany; (3) Department of Physics and Chemistry, University of Southern Denmark, Campusvej 55, DK-5230 Odense M, Denmark  
When Nature goes beyond the central limit theorem: from gene control to animal foraging                                                                           (l)

Vincenzo Capasso, Alessandra Micheletti, Davide Morale
ADAMSS and Department of Mathematics, University of Milano, Via
Saldini 50, 20133 Milano, Italy
Stochastic Geomatry and related statistical issues in the mathematical modelling of tumor-induced angiogenesis                                             (p)

Agnieska Kitlas (1), Marta Borowska (1), Edward Oczeretko (1), Marek    Kowaleski (2) , Miroslaw Urban (2)
(1) Institute of Computer Science, University of Bialystok, Sosnowa 6       15-887  Bialystok,   Poland, (2) 2-nd Department of Children Disease,  Medical University of Bialystok Waszyngtona17, 15-274 Bialystok, Poland
Lempel-Ziv complexity measure and approximation entropy in the analysis of the heart rate variability in children.                                                    (p)

Alexander Delides
Athens Medical Center, Athene   Greece
Fractals and Sleep: Fractal Quantitative Endoscopic Analysis of the upper airway as a predictor for Obstructive Sleep Apnea Syndrome                     (p)

Marta Borowska (1), Edward Oczeretko (1), Piotr Sobaniec (2)        Tadeusz  Laudanski (3)
(1) Department of Medical Informatics
, Institute of Computer Science, University  of  Bialystok, Sosnowa 64, 15-887 Bialystok, Poland
(2 )Department of Electrical Engineering, Technical University of Bialystok, Wiejska  45D, 15-351 Bialystok, Poland; Neurology Student's Society, Department of Children Neurology, Medical University of Bialystok. Waszyngtona 17,15-274 Bialystok,  Poland
(3)Department of Pathophysiology of Pregnancy, Medical University of 
Bialystok, MSkłodowskiej-Curie 24a, 15-273, Bialystok, Poland

Synchronization in multivariate biomedical time series-nonlinear dynamics.  (p)

Mircea V. Rusu 
Department of Atomic and Nuclear Physics, Faculty of Physics, University of Bucharest, Bucharest, Romania
Aspects of
pattern formation outside of equilibrium.                               (p)


6.30  pm                 San  Francesco’s  Church

Maestro Livio Vanoni 
Organ Concert:
  Music of  Johann Sebastian Bach

8.00  pm                 Fractal  Dinner-Sympósion

                              Albergo Elvetico Locarno

       Melodie Immortali  

       Trio Alvaros







                                                        Saturday  March  15, 2008


9.30  am                Session  VII     

                                      Chairman:  Sandro  Rusconi  Bellinzona  CH

     Invited speaker: 

                 Fabio Grizzi
                 Istituto Clinico Humanitas, Rozzano - Milano   Italy

                 < The fractal design of  human anatomy  in the era of system biology >    (l)

10.15 am               Invited speaker: 

                             Rangaraj M. Rangayyan
                             Department of Electrical and Computer Engineering
                             University of Calgary, Calgary,  Canada 

                            < Fractal diagnosis of  breast tumours from radiographic  images >           (l)

11.00 am               Pause

11.30 am               Invited speaker:

                             Andras Eke
                             Institute of Human Physiology and Clinical Experimental Research,
                             Semmelweis  University, Budapest   Hungary

                             < Fractal physiological time series analysis: from methods to applications in
                             assessment of  perfusion dynamics in the human brain cortex from the    
                             standpoint  of age, gender and localization >                                         (l)

12.15 pm              Chairman :  Theo F. Nonnenmacher  Ulm  DE
                             Conclusions,  Comments 


End of the Fifth Symposium